A lot of things need to go right on a molecular level for immune cells to launch an adaptive response to an infection. B ...

Teleost fish represent a diverse group of bony vertebrates distinguished by a fully functional adaptive immune system. Their lymphoid tissues—principally the thymus, head kidney and spleen—support the ...

Building upon a deep understanding of immune cell activation, researchers from Children's Hospital of Philadelphia (CHOP) developed a new artificial platform that can be used to induce T cell ...

A new review by Dr. Ruyuan Wang and an international team of researchers explores the complex interactions between the innate and adaptive immune systems, shedding light on regulatory mechanisms in ...

The concept of trained immunity has redefined innate immune responses as adaptable, durable, and context dependent. Natural killer (NK) cells, traditionally ...

Scientists generally agree that eukaryotes, the domain of life whose cells contain nuclei and that includes almost all multicellular organisms, originated from a process involving the symbiotic union ...

A new study highlights the role of natural killer T cells in influencing the immune response to dengue virus, potentially reducing the severity of subsequent infections. As the dengue virus continues ...

Autoimmune and autoinflammatory diseases have traditionally been interpreted as disorders arising from dysregulation of adaptive or innate immune responses, ...

Antibodies, which recognize viruses and proteins that the body has encountered before, have long gotten most of the credit for giving the human immune system a memory. Now, researchers at the ...

A new Review reveals how aging can push the immune system into a paradoxical state, weaker against threats yet more prone to attacking the body’s own tissues.