A research team at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan report they have created a model of the blood-brain barrier using modularized tissue derived from human cells. The ...
A research team at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has succeeded in establishing a model of the blood-brain barrier using modularized tissue derived from human cells.
CANDID-CNS™ is the new state-of-the-art AI model for BBB penetration: it achieves 87% AUPRC on bRo5 small molecules compared to 56% by Pfizer’s ...
- CANDID-CNS TM achieves an 83% success rate for predicting small molecule brain penetration and distribution versus a 64% success rate for the industry standard CNS-MPO score - Only ~2% of small ...
Scientists from the University of Liverpool and their global collaborators have highlighted the most effective treatments for neurological diseases by overcoming one of medicine's most difficult ...
A TTUHSC research team published new evidence suggesting that the blood-brain barrier (BBB) remains largely intact in a commonly used mouse model of Alzheimer’s disease. Ehsan Nozohouri (seated), a ...
While this protects the brain from external threats, it also presents a major challenge for treating neurological diseases, as many potentially therapeutic compounds are unable to cross. One potential ...
Focused ultrasound with microbubbles is a noninvasive procedure that transiently opens the blood-brain barrier (BBB) using low-intensity sound waves. The openings reseal within 24 hours. Using MRI to ...
BOSTON, Dec. 05, 2025 (GLOBE NEWSWIRE) -- 1910, the only AI-native biotech pioneering small and large molecule therapeutics discovery, today announced that its CANDID-CNS (TM) AI model has been ...
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