Sickle cell disease is a devastating, inherited blood disorder that affects an estimated eight million people worldwide and ...

An international collaboration study reveals how evolution and locomotion patterns, such as bipedalism, shaped bone ...

Among adults with evidence of systemic mast cell activation, bone marrow samples allowed for detection of 13 additional ...

At the Cleveland Clinic, doctors are using a one-time gene-editing therapy that alters a patient’s own blood-forming stem cells to correct the genetic mutation responsible for the disease. Physicians ...

Chimeric antigen receptor-T cell (CAR-T cell) therapies have been a significant advance in the field of cancer immunotherapeutics in recent years, particularly for B-cell malignancies. Yet, this ...

Researchers recently developed a bone marrow model to study how the body generates cells. Interestingly, this model is the first of its kind to be developed entirely from human cells. Not only can ...

Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects ...

A University of Kentucky Markey Cancer Center study reveals how prostate cancer cells adapt their metabolism to thrive in ...

Normal, regulated growth of skeletal bones is a crucial part of the growth of mammals. This is a complex process involving ...

Hypertrophic chondrocytes are deeply involved in the growth of mammalian bones. Researchers find that these cells transform ...