Problems with the brain’s ability to ‘prune’ itself of unnecessary connections may underlie a wide range of mental health disorders that begin during adolescence, according to research published today ...

A new study from Austrian researchers suggests the brain begins life with an overly dense and disorganised network of ...

Adolescence is widely thought to be a time when the brain trims away excess neural connections, refining circuits through synaptic pruning. New research now suggests this view may be incomplete.

Many disparate conditions, such as depression, phobias and attention deficit hyperactivity disorder (ADHD), may have the same underlying cause: a delay in “pruning”, a process in which unneeded ...

A new Nature Communications study reveals that mouse hippocampal CA3 circuits start life as dense, randomly connected networks before shedding many synapses to form sparse, organized structures suited ...

If you scroll through TikTok or Instagram long enough, you’ll inevitably stumble across the line: “Your frontal lobe isn’t fully developed yet.” It’s become neuroscience’s go-to explanation for bad ...

Placebo pain mapped: UC San Diego scientists identified a brain circuit in mice where expectation triggers opioid release to relieve pain, offering clues for human therapies. Core-brain link: Penn ...