CSF-ctDNA was detected in 59% of cases and showed high concordance (84%) with tumor mutations. Lower variant allelic frequency in CSF-ctDNA was associated with significantly worse survival outcomes.

Tailored Approaches in the Treatment of Patients With Colorectal Cancer Harboring Tropomyosin Receptor Kinase Fusion and Microsatellite Instability-High: A Case Report and Literature Review ...

A CSF leak within the spinal column is the most common identifiable cause of spontaneous intracranial hypotension. 3 The mechanism underlying headache and neurologic manifestations is presumed to be ...

Sequencing circulating tumor cell-free DNA (cfDNA) in cerebrospinal fluid (CSF) improved diagnosis, decision-making, and clinical care in pediatric and adolescent and young adult (AYA) patients with ...

On Fridays and some Tuesdays, neurosurgeons in Kuopio place ventriculo-peritoneal shunts. During the procedure, they collect biopsies of skin, fat, muscle, right frontal cortex, intraventricular CSF.

The Association of Primate Veterinarians (APV) recognizes that CSF collection may be required for both clinical and research purposes in nonhuman primates (NHP). Because there are inherent risks ...