Scientists at the Electron Bio-Imaging Centre (eBIC) at Diamond Light Source, in the U.K., have harnessed a new technique, using cryo-electron tomography (cryoET) and subtomogram averaging (STA) to ...

Though treatments are available, there is no cure or vaccine from HIV, which impacts about 38 million people worldwide. It's difficult to target the RNA genome of the HIV virus in part because it ...

Cryo-electron microscopy has given scientists the first glimpse at how the measles virus wraps up its genome in its protective protein container. The 4.3-Å structure provides a platform for ...

The outer shells – or capsids – of viruses contain proteins, which are made of a string of building blocks called amino acids. Proteins fold into specific shapes, depending on the sequence of amino ...

A new technique using electron tomography and subtomogram averaging at Diamond's electron Bio-Imaging Centre (eBIC), has solved the structure of the HIV capsid alone and in complex with host factors.

Scientists have provided a close-up look at the cone-shaped shell that is the hallmark of human immunodeficiency virus, revealing how it is held together -- and possible ways to break it apart. New ...

Many pathogenic viruses require a specific structure to be infectious, and their proteins form that structure in vivo with remarkable fidelity. The dynamical process by which protein conformations are ...

With up to 2.4 million U.S. cases and over 250 million chronic cases globally, hepatitis B infection persists despite the availability of a vaccine. Vaccines work by immunizing the body against a ...

A new technique using electron tomography and subtomogram averaging at Diamond’s electron Bio-Imaging Centre (eBIC), has solved the structure of the HIV capsid alone and in complex with host factors.