Natural killer (NK) cells are pivotal in the innate immune response against cancer and viral infections, with their presence in tumors correlating to better patient outcomes in various cancers.

Researchers in the lab of Jean Cook, Ph.D., chair and professor in the Department of Biochemistry and Biophysics, have identified the cellular processes that occur when you take a cancer drug meant to ...

A new comprehensive review reveals that harnessing natural killer (NK) cells by blocking their “off-switches” could significantly enhance cancer immunotherapy, providing new avenues for treating solid ...

Yale researchers have uncovered a way to make a type of white blood cells known as natural killer cells — which kill infected, damaged, or malignant cells in the body — more effective against cancer.

This Research Topic is Volume II of a series. The previous volume, which has attracted over 21k views can be found here: New Tumor Immune Checkpoints and ...

Combined epigenetic and immune checkpoint therapy altered the tumour microenvironment in platinum-resistant ovarian cancer.

Immune checkpoint inhibitors are cancer therapeutics that have shown remarkable success in extending lives in many cancers, including melanoma, MSI-high cancers, and other cancers. However, these ...

After months of shrinking scans, the tumors suddenly came roaring back. Oncologists have seen this pattern for years in ...