Explore the role of transcription factor biology in drug discovery and how it impacts our understanding of disease mechanisms ...

The re-transcribed DNA is then integrated into the genome of the host cell (Figure 2). This process requires the absence of the nuclear membrane and thus is restricted to the M-phase of proliferating ...

New capital will support ongoing development of their drug pipeline targeting transcriptional mechanisms in disease Arpeggio’s technology isolates a drug’s effect on entire transcriptomes and has ...

Peer-reviewed discovery platform and data in PNAS show that single transcription factor modulation reverses aging-associated gene expression and restores healthy cellular and tissue function in models ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...