A specific pattern of brain activity in a frontal brain region is linked to compulsive behaviors like excessive hand washing, chronic hair-pulling, and skin-picking in people with obsessive compulsive ...

A high-frequency brain signal in the frontal cortex is linked to OCD compulsions. Targeted deep brain stimulation rapidly reduced symptoms in severe cases.

As humans and other animals navigate their surroundings and experience different things, their brain creates so-called cognitive maps, which are internal representations of environments or tasks.

Study reveals how aging accelerates molecular changes in the brain, offering new hope for tackling cognitive decline and mental illness. Resource: Single-nucleus transcriptomic profiling of human ...

A new study links anxiety, a brain structure called the orbitofrontal cortex, and optimism, finding that healthy adults who have larger OFCs tend to be more optimistic and less anxious. The new ...

Overexpression of Shisa7 in the orbitofrontal cortex in drug-free rats induced comparable up and down changes in gene expression as that induced by the self-administration of heroin. The concordant ...