Canadian Medical Association Journal

Severe maternal morbidity from conception to 6 weeks postpartum in Ontario: a population-based, longitudinal cohort study

Background: Although severe maternal morbidity (SMM), such as severe hemorrhage and sepsis, can occur from conception to 6 ...
Medical Xpress

Quantitative Concept: Cohort Studies

Maternal influenza and tetanus-diphtheria-acellular pertussis (Tdap) vaccinations are associated with a lower risk for influenza- and pertussis-related hospitalization or emergency department (ED) ...
BMJ

Do the associations of daily steps with mortality and incident cardiovascular disease differ by sedentary time levels? A device-based cohort study

4 Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Providencia, Chile 5 Universidad de Santiago de Chile (USACH), Escuela de Ciencias de la Actividad Física, el Deporte y la Salud, ...
ascopubs.org

Using Dose-Escalation and -Expansion Cohort Study as Pivotal Trial for Targeted Anticancer Drug Approval

BRCA1-Associated Protein 1 and Enhancer of Zeste Homolog 2: Pathway Interaction and Therapeutic Intervention in Breast Cancer, Mesothelioma, and Lymphoma Early-phase clinical trials (EPCTs) have been ...
BMJ Open Sport & Exercise Medicine

Association of physical fitness and overweight with mental and behavioural diagnoses in a population-based cohort of 156 202 young men

Objectives Declining physical fitness, rising obesity and mental and behavioural diagnoses are growing public health issues in young adults. This study aimed to examine the associations between ...
RMD Open

Autoantibody biomarkers and first-line therapy response in RA: findings from the CAP48 cohort

Objective A panel of antibodies against three antigens, University Hasselt (UH)-rheumatoid arthritis (RA).305, 318 and 329, has been associated with lack of response to first-line therapy in the Care ...
BMJ

Cardiorespiratory fitness is a strong and consistent predictor of morbidity and mortality among adults: an overview of meta-analyses representing over 20.9 million observations ...

Objective To examine and summarise evidence from meta-analyses of cohort studies that evaluated the predictive associations between baseline cardiorespiratory fitness (CRF) and health outcomes among ...