Aptamers are single-stranded oligonucleotides generated by the systematic evolution of ligands by exponential enrichment (SELEX). They have a wide variety of applications, but computational approaches ...

WEST LAFAYETTE, Ind. — About 50% of people who take the drug infliximab for inflammatory bowel diseases, such as Crohn’s disease, end up becoming resistant or unresponsive to it. Scientists might be ...

Scientists from the Icahn School of Medicine at Mount Sinai, working in collaboration with a team from the University of Texas at El Paso, have developed a novel computational framework for ...

Stephen Wolfram has had the sort of career that The Big Bang Theory's Sheldon Cooper might identify with: PhD in particle physics at 20, youngest-ever MacArthur Fellow at 21. At 26, Wikipedia tells us ...

Biomedical engineers at Duke University have significantly enhanced the capabilities of a computational model that simulates the movement of individual cancer cells across long distances within the ...

Genetic diseases that result from truncated proteins can be targeted by so-called nonsense suppression therapies—drugs that prevent protein translation from terminating prematurely. A new ...

Scientists have developed a new computational model showing how the brain maintains information short-term using specific types of neurons. Their findings could help shed light on why working memory ...

Through advantageous mutations that can occur at the virus’s spike protein, tests have shown that the emergence of several new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ...

Oligonucleotides are short, single strands of synthetic DNA or RNA. Albeit small, these molecules play an important role in molecular and synthetic biology applications. One type of ...