To generate a tissue specific knockout mouse, researchers breed a mouse bearing a Cre transgene under a tissue- or cell-type specific or inducible promoter (A) with a homozygous floxed mouse (B). The ...

To discover the function of a gene researchers turn it off and observe the consequences. Often genes have multiple functions that differ depending on a tissue and age. Some genes are essential to ...

Unlike many site-specific recombinases that require accessory proteins, the Cre recombinase itself organizes a synaptic complex to initiate the recombination reaction. A new study suggests how Cre ...

AIIMS CRE 2025: The All India Institute of Medical Sciences (AIIMS), New Delhi has started the application process for the Common Recruitment Examination (CRE) 2025. This exam is being conducted for ...

Stainless Steel hardware is prone to galling. Stop galling with LOX-8. Use LOX-8 Thread Sealant or LOX-8 Lubricant to prevent galling Trusted Solution for Threaded Connections in Demanding ...