Michael Buck, PhD, professor of biochemistry in the Jacobs School, recently received NIH funding to explore how molecular readers of DNA access and activate seemingly hidden genes.

MIT researchers discovered that the genome’s 3D structure doesn’t vanish during cell division as previously thought. Instead, tiny loops called microcompartments remain (and even strengthen) while ...

Every cell in the body has the same DNA, but different cell types—such as muscle or brain cells—use different parts of it.

The accuracy of transcription processes varies widely among species, across cell types and within distinct regions of the genome, with profound consequences for health and disease.DNA transcription is ...

RNA Polymerase (shown in blue) moves across a template strand of DNA (shown in purple) and transcribes it into RNA (shown in red). But DNA damage blocks the RNA polymerase, causing it to stall and ...

As illustrated with OnScreen Gene Transcription in our May 1 column, OnScreen Science now has a few very nice iPad apps to teach students about DNA and RNA. The OnScreen DNA Model app was the original ...

Every living cell must interpret its genetic code - a sequence of chemical letters that governs countless cellular functions. A new study by researchers from the Center for Theoretical Biological ...