JAK2 belongs to the Janus family of cytoplasmic tyrosine kinases (JAK1–JAK3, TYK2) and functions as a crucial mediator of signaling for hematopoietic cytokines and hormones such as erythropoietin (Epo ...
Regulated protein transport between the cell surface and distinct intracellular compartments of the endo- and exocytic apparatus is a crucial determinant of cellular function. Proper protein ...
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