Drugs for inflammatory conditions drove nearly half of spending in commercial plans last year, a new report shows. Express Scripts released its annual Drug Trend Report, which analyzes costs and ...

Eliminating the protected classes of medications for Medicare Part D plans could give insurers more leverage to negotiate rebates, but may have a limited financial payoff, according to a new analysis.

The federal government has backed off a proposal that would have let Medicare Part D prescription drug plans deny coverage for therapies in six "protected" classes of drugs, including those for cancer ...

Scientists have identified two molecules that could help treat leukemia, in a way that’s far less damaging to healthy cells than existing chemotherapy. The compounds work using a different mechanism ...

Researchers looked specifically at head-to-head randomized clinical trials of next-in-class cancer drugs against existing agents in the same class. Less than one-quarter of next-in-class cancer drugs ...

Nitazenes, like this powder sample, are a class of synthetic opioids more potent than morphine and fentanyl. Joe Lamberti/The Washington Post via Getty Images Nitazenes are psychoactive substances, or ...

Oveporexton, a novel first-in-class OX2R-selective agonist, shows promise for improving memory, attention, and executive function in individuals with narcolepsy type 1.

Two new classes of HIV drugs are poised to hit the market in 2007, signalling what many say is a watershed in HIV treatment, second only to the introduction of cocktail therapy more than a decade ago.

Researchers studying new methods for improving blood sugar control in type 2 diabetes have discovered an old class of antipsychotic drugs may offer clues to a novel kind of treatment for hyperglycemia ...

An experimental Viking Therapeutics obesity drug that hits the same targets as a commercialized Eli Lilly medication has clinical data showing it led to an average 13.1% weight loss after 13 weeks of ...