To mark the 50 th anniversary of the discovery of the three nuclear RNA polymerases, we feature a collection of Perspective and Review pieces that narrate the history of eukaryotic transcription ...

The Royal Swedish Academy of Sciences has awarded the Nobel Prize in Chemistry for 2006 to Roger D. Kornberg of Stanford University "for his studies of the molecular basis of eukaryotic transcription.

This image illustrates the process of gene transcription within a cell. The DNA double helix unwinds to expose a specific sequence, allowing RNA polymerase to synthesize a complementary pre-mRNA ...

The central dogma of molecular biology dictates that information flows from DNA into RNA into protein in living cells. Transcription, a major tenet of this dogma, is the process by which information ...

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The regulation of mRNA transcription plays a key role in relaying signals from the environment and during development into the gene expression program of a cell. During transcription initiation, a ...

In eukaryotic gene expression, the mRNA transcript produced by transcription of DNA undergoes a series of processes such as splicing, 3’ polyadenylation, and 5’ capping, all of which helps in making ...

Genes can be turned on and off as needed to adapt to environmental changes. But how do the different molecules involved interact with each other? Scientists present a candidate mathematical model for ...

Proteins are essential biological molecules that perform a vast array of functions crucial for life, from catalyzing ...