Congenital fibrinogen disorders encompass a heterogeneous group of inherited conditions affecting either the quantity or quality of fibrinogen, a critical glycoprotein in the coagulation cascade.

THE appearance of a severe hemorrhagic diathesis associated with the absence, or extremely low levels, of circulating fibrinogen has long been known in certain clinical conditions such as premature ...

Fibryga was found to be noninferior to cryoprecipitate based on the total number of units of allogeneic blood products administered during the first 24 hours after termination of cardiopulmonary ...

Before soluble fibrinogen, a blood plasma protein, is converted into insoluble fibrin molecules that can toxically accumulate outside blood vessels in the brain, fibrinogen connects directly with ...

The conversion of fibrinogen to fibrin, the final step in the blood coagulation sequence, is a complex but orderly reaction. Thrombin cleaves the long, axially oriented fibrinogen molecule at a ...

Researchers have discovered the influence of the coagulation factor fibrinogen on the damaged brain. Neural stem and progenitor cells (NSPCs), from the so-called subventricular zone (SVZ), can help to ...

These drugs, which are among the most common types of blood thinners, can interfere with traditional coagulation tests, producing unreliable results.

New research reveals that fibrin, a key component of blood clots, may be the secret culprit behind the devastating neurological and inflammatory aftermath of the virus, including long COVID. From ...

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