A new CRISPR approach can control genes without cutting DNA, opening a safer path for treating genetic diseases. A newly ...

SCD gene therapy approaches using CRISPR, gene therapy, and base editing show different stem cell outcomes in a mouse study.

Every year, millions of lives are suddenly, swiftly transformed by a stroke, which occurs when a blood vessel travelling ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...

Cell and gene therapies use the body's building blocks - cells and genetic material - to boost the immune system or correct ...

CAR T cells are patient-derived, genetically engineered immune cells. They are "living drugs" and constitute a milestone in modern medicine. Equipping T cells, a key cell type of the immune system, ...

Sickle cell disease (SCD) is a group of genetic blood disorders. A person inherits SCD from their parents when they inherit two copies of the sickle cell gene, one from each parent. This hereditary ...

Genetic defects are exceedingly common, which is not surprising considering just how many cells make up our bodies, including our reproductive cells. While most of these defects have no or only minor ...

Scientific organizations recently called for a 10-year ban on human germline editing. But will we ever be ready? And how would we even know? Reading time 13 minutes In late May, several scientific ...