In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems. Now an interdisciplinary ...
This story is part of a series on the current progression in Regenerative Medicine. In 1999, I defined regenerative medicine as the collection of interventions that restore tissues and organs damaged ...
There are probably around 20,000 genes in the human genome that code for protein, and cells have to transcribe DNA sequences into RNA, which is then processed before it is translated into proteins by ...
Delivery of therapeutic genes is essential for gene therapy. Adeno-associated viruses (AAVs) are a prime vector for carrying ...
New research shows that a large, ubiquitous mobile genetic element changes the antagonistic weaponry of Bacteroides fragilis, a common bacterium of the human gut. Bacteria evolve rapidly in the human ...
The ability to control the expression of therapeutic genes within a “therapeutic window” is crucial to ensure the development of safe and effective gene therapies, but to date, there has been no ...
In a recent study published in the journal Nature, scientists used mouse models to test whether in vivo gene silencing is sustained after transient delivery and expression of engineered ...
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