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A new study finds that proteins known as linker histones control the complex coiling process that determines whether DNA will wind into long and thin chromosomes, made up of many small loops, or short ...
Targeting a specialized group of histones is safe and opens new therapeutic opportunities for treating blood cancers, a new ...
Histones are a family of basic proteins that associate with DNA in the nucleus and help condense it into chromatin. Nuclear DNA does not appear in free linear strands; it is highly condensed and ...
UCLA scientists have identified a new function for histones, the spool-shaped proteins that regulate gene expression and serve as anchors for strands of DNA to wrap around. The researchers discovered ...
Finding a needle in a haystack is hard enough. But try finding a specific molecule on the needle. Rice University researchers have achieved something of the sort with a new genome editing tool that ...
Histones are proteins that are used to organize and compact DNA. Some giant viruses called Marseilleviridae, which infect amoebas, have also been found to use histones; they wind their DNA around ...
In our cells, 6 feet (1.8 m) of DNA gets crammed into chromosomes that fit inside a 6-µm-wide nucleus. The proteins that help pack up that genetic material are histones, which act as spools around ...
The development of new strategies to deplete maternal histone proteins in vivo and in vitro has led to the discovery of unexpected roles of histones in forming a functional nuclear envelope. Proteins ...
Forbes contributors publish independent expert analyses and insights. Carly is a geoscientist reporting scientific innovation and discovery. Once dissolved (or "demineralized"), some well preserved ...
Lung fibrosis is a debilitating disease affecting nearly 250,000 people in the U.S. alone with 50,000 new cases reported each year. There is currently no cure and limited available treatment options, ...
Targeting a specialized group of histones is safe and opens new therapeutic opportunities for treating blood cancers. This is the main finding of the latest research by Dr. Marcus Buschbeck and Dr.