Scientists have uncovered a gut-specific epigenetic aging mechanism that links inflammation and iron imbalance to cancer risk and may be reversible.

Human organoids are 3D cell cultures derived from adult stem cells and maintain the variable distribution of epithelial cells seen in primary tissue. They can recapitulate the mechanisms of epithelial ...

Tuft cells are present throughout the intestinal tract as well as in many organs. Studies in mice have shown that when tuft cells sense the presence of pathogens, they signal to immune cells and to ...

Gastric cancer cells can activate KRAS-driven signals, enabling autonomous tumor growth by producing their own WNT proteins. New research reveals how gastric cancer cells exploit WNT signaling for ...

Bowel cancer risk is influenced by several overlapping factors including age, weight and inflammation. This study is early stage biology, but it strengthens the idea that long term gut health is ...

Researchers have found that CAR T-cell therapy can help aging intestines heal by targeting senescent cells. In mice, it ...

The human small intestine absorbs nutrients while protecting us from potentially harmful microbes. One of the cell types that plays a key role in this protection is the microfold cell (M cell). These ...

Altered intestinal barrier function is postulated to be a central predisposing factor to intestinal diseases, including inflammatory bowel diseases and food allergies. However, the mechanisms involved ...

Stomach cancer, also known as gastric cancer, begins in the cells that line the stomach. The vast majority of stomach cancers are the adenocarcinoma type, which affects the glandular mucus-producing ...

Small intestine cancer occurs when abnormal cells grow in the tissues of the small bowel, the long tube that connects your ...