Innovative approaches to controlled nucleobase-modified RNA synthesis are urgently needed to support RNA biology exploration and to synthesize potential RNA therapeutics. Here we present a strategy ...
This course will give an introduction to the theory and practice of analyzing high-throughput RNA sequencing through lectures and hands-on exercises. The basic topics covered will include: 1) the ...
Single-cell technology has revolutionized the field of biological research by enabling the analysis of individual cells, providing unprecedented insights into cellular heterogeneity and function. More ...
RNA base editing relies on the introduction of adenosine-to-inosine changes into target RNAs in a highly programmable manner in order to repair disease-causing mutations. Here, we propose that RNA ...
Researchers at the University of Ottawa may have cracked the code to harness both mRNA and RNAI-based therapies to improve the treatment of cancer, cardiovascular and other complex diseases. The ...
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