In the mammalian CNS, the principle excitatory neurotransmitter is L-Glutamate, which acts through G-protein coupled (metabotropic) receptors and ligand gated ion channels (ionotropic receptors).
The brain’s major excitatory neurotransmitter is glutamate. Glutamate, which is released from presynaptic vesicles, is the neurotransmitter which activates postsynaptic ligand-gated ion channel ...
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