The mesenchyme plays a crucial regulatory role in organ formation and maintenance. However, comprehensive molecular characterization of these cells is lacking. We found unexpectedly that primary ...

Hepatocyte nuclear factor-1β (Hnf1 β) is associated with early embryogenesis failure, renal cysts, and/or diabetes. However, factors regulating Hnf1 β expression in metanephric mesenchyme cells remain ...

HIF-2 is a heterodimer of two proteins, HIF-2α and HIF-1β 3. HIF-1β is constitutively expressed, whereas HIF-2α is the hypoxia-responsive component of the complex. The other HIF-α isoform is HIF-1α.

A few models have been established to study cancer cells in vitro. However, the cellular interactions have rarely been studied specifically using bioengineered cancer constructs combining human ...

Lung mesenchymal cells, which are critical components of the lung’s unique structure, also play important roles in disease and recovery from injury, yet knowledge is limited about their biology or how ...

We applied swim flume-mediated exercise during zebrafish caudal fin regeneration to explore mechanical loading impacts on a robust model of organ regeneration. Exercise initiated during but not after ...