Conserved cysteine residues on the matrix-facing loop of SLC25A39 are essential for sensing mitochondrial glutathione. (A, B) Immunoblots for the indicated proteins in HEK293T cells expressing ...

Using new super-resolution microscopes, researchers at the University of California, Irvine and the University of Pennsylvania have for the first time observed electrical charge and discharge ...

James McCully was in the lab extracting tiny structures called mitochondria from cells when researchers on his team rushed in. They’d been operating on a pig heart and couldn’t get it pumping normally ...

The components of cells that provide them with energy may play an unexpected role in sleep. A study in fruit flies suggests that mitochondria in the brain help trigger sleep when they sense that the ...

Scientists have discovered how mitochondria sense and control their glutathione levels, an antioxidant produced throughout the body. The first nutrient-sensing mechanism identified for an organelle, ...