A phase Ib study of telatinib (BAY 57–9352), a VEGFR-2 inhibitor, in combination with docetaxel in patients with advanced solid tumours ...
Healio spoke with Ahmad Anouti, MD, a pediatric resident at UT Southwestern Medical Center, about a presentation at The Liver Meeting on how blocking nuclear factor kappa B could correct cellular ...
Researchers at National Taiwan University Hospital in Taipei have conducted a study demonstrating the potential effectiveness of a novel drug combination at reducing morbidity and mortality in ...
DNA repair, multidrug resistance and metabolic enzyme genes polymorphisms as predictors of clinical outcome in resected non-small cell lung cancer (NSCLC) ...
COLD SPRING HARBOR, N.Y. (May 25, 2010) --NF-κB is a critical signaling molecule in the immune system that regulates cell survival and cell death, lymphocyte responses, and inflammation. Acting as a ...
Endosomal stress, the aberrant accumulation of K63 ubiquitin chains on dysfunctional endosomes, activates the TAB2/3–TAK1–NF-kB and p62–Keap1–Nrf2 pathways, resulting in the expression of immune and ...
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