Genetic research uncovers a continuum between diabetes forms, offering insights for precision medicine. Study: Rare variant analyses in 51,256 type 2 diabetes cases and 370,487 controls reveal the ...

In this groundbreaking study, researchers uncover how ultra-rare genetic variants, especially in heart cells, play a critical role in raising the risk of coronary artery disease among individuals of ...

Researchers have introduced an algorithm based on deep learning that can predict the effects of rare genetic variants. The method allows persons with high risk of disease to be distinguished more ...

The study, titled “Association of IgG4-Related Disease with Human Inborn Errors of Immunity,” involved 18 patients diagnosed with IgG4-RD, all of whom underwent Whole Exome Sequencing (WES) to examine ...

ADHD is a neurodevelopmental disorder with a high heritability, in which the genetic component consists of thousands of genetic variants. Most variants only slightly increase the likelihood of ...

People with rare genetic variants that are linked to Parkinson’s disease and other neurodegenerative disorders have a higher risk for developing amyotrophic lateral sclerosis (ALS), also called Lou ...

Whether we are predisposed to particular diseases may depend to a large extent on variations in our genomes, but the influence on the presentation of certain pathological traits of genetic variants ...

A genetic method has been developed to cluster distantly related people, identifying rare genetic variants that can be used to find cases of undiagnosed genetic disease. Researchers from Vanderbilt ...

Genetic inheritance may sound straightforward: One gene causes one trait or a specific illness. When doctors use genetics, it’s usually to try to identify a disease-causing gene to help guide ...