Amphotericin B produces chills and fever in a significant proportion of patients who receive this drug. The mechanism for this adverse effect is unknown. Amphotericin B suspension at a concentration ...

An extremely short way to prostaglandins has been opened by combining the newly devised organometallic methodologies. Convergent, one-pot creation of the prostanoid framework is achieved by ...

Although the effects of anti-inflammatory drugs have been well studied, little is known about the signaling pathways involved in the inflammatory response. The recent finding that cyclopentenone ...

Prostaglandins been linked to the sensory perception of pain, but their role in the emotional response to pain is unclear. A new study has demonstrated that the aversive effects of inflammatory pain ...

Construction of cyclopentanes constitutes an area of significant interest in the organic community 1,2,3, as evidenced by numerous campaigns towards landmark natural products, including the ...

Resveratrol (trans-3, 5, 4'-trihydroxystilbene) is a polyphenol found in many plants and in the red wine that reveals several pharmacological actions, including anti-inflammatory properties. Recent ...

Peripheral T-cell lymphoma (PTCL) is an aggressive tumor derived from mature T cells and natural killer cells with an extremely poor prognosis. Ferroptosis is a mechanism of cell death that is ...

Prostaglandins play a role in numerous biological processes, including sleep, pain, fever, inflammation, menstruation, birth, constriction of blood vessels, and blood clotting. The prostaglandin ...

The effects of aspirin, nonspecific nonsteroidal anti-inflammatory drugs (NSAIDs), and cyclooxygenase (COX)-2 specific inhibitors on prostaglandins (PGD2, PGF2a, PGE2, PGH2) synthesis PGI=prostacyclin ...