Increased colonic K + excretion through inhibition of the H,K-ATPase type 2 helps reduce plasma K + level in a murine model of nephronic reduction Figure 2: WNK4 reduces surface expression of ROMK.

A WNK and a nod In light of the identified actions of wild-type and mutant WNK4, we may now be able to explain at the molecular level the nephron's ability to control independently sodium-chloride ...

The pattern of transport of penicillin G and carbenicillin was examined directly in the rat kidney by means of micropuncture studies. Samples of plasma, tubular fluid, and urine were assayed for ...

Type 2 diabetes is a major health problem in the 21st century, with increasing rates of obesity both driving up the number of patients affected and reducing the age at diagnosis. Drugs that lower the ...