THE volume under review is the fourth edition, revised and enlarged, of a “Biological Monograph” first published in 1925. As the editors point out, “Conspicuous progress is now being seen in the field ...

Through tumor profiling and statistical analysis, precision oncology uses genomic and other biomarkers to drive discovery, drug development, and clinical care for patients with cancer. It intends to ...

Outliers may provide useful information about the development and manufacturing process. Analysts use various statistical methods to evaluate outliers and to reduce their impact on the analysis. This ...

Statistical methods now being used in adaptive biomarker-driven clinical trials are reviewed. Some previous paradigms for clinical trial design can limit the development of more effective methods on ...