Just like workers need the right environment to efficiently perform their tasks, proteins require placement within specific cellular compartments to function properly. Therefore, understanding where ...

A newly discovered nuclear role for HSL reveals how imbalances in its location within fat cells may contribute to both ...

Localizatome contains comprehensive information about the stress-induced protein localization changes within living cells. It provides open access to subcellular protein localization data through a ...

In the fast-evolving field of medical science, a new artificial intelligence model may be about to change the way mRNA-based drugs and vaccines are designed. Developed through a collaboration between ...

The centrosome serves as the microtubule-organizing center and plays a critical role in cell division. Centrosomal RNAs (cnRNAs) have been reported to enable precise spatiotemporal control of gene ...

The first-in-human phase 1/2 study of TSN1611, a highly selective KRAS G12D inhibitor, in patients with advanced solid tumors. Seizure-related homolog 6 (SEZ6) expression and ctDNA methylation ...

Researchers developed a new machine learning method that, given a relevant amino acid sequence, can automatically predict the location of a protein in any human cell line down to the single-cell level ...

An MIT-based team has developed a technology pipeline that creates whole-organ, high-quality images of human brains from the gross morphological level to subcellular components. The technique enables ...

Molecular and immunological characterization of androgen receptor expression in different breast cancer subtypes. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This abstract ...