Erectile function was assessed 6 weeks following uni- and bilateral injections of 6-hydroxydopamine in the substantia nigra nucleus of the brain. Behavioral apomorphine-induced penile erections were ...

Researchers at Karolinska Institutet, Columbia University and the University of San Francisco, have uncovered a previously ...

Parkinson's disease (PD) is an age-related, progressive neurodegenerative disorder. The hallmark of PD pathogenesis is the ...

Parkinson's disease is a progressive neurological disorder characterized primarily by motor symptoms that include rigidity, hypokinesia and tremor. The most pronounced neuropathological feature is a ...

New research has uncovered a previously unknown mechanism by which dopamine, a key brain chemical vital for movement and ...

New therapy targeting a small brain region boosts levodopa’s effects Damage to powerplants in dopamine neurons triggers Parkinson’s disease Goal to identify people who will develop Parkinson’s in five ...

Parkinson's disease (PD) is an age-related, progressive neurodegenerative disorder. The hallmark of PD pathogenesis is the ...

Scientists have uncovered new molecular drivers of Parkinson's disease using a sophisticated statistical technique called multiscale gene network analysis (MGNA). The team was also able to determine ...

Stimulating the ventral tegmental area, one of two dopamine-producing regions in the brain, was able to arouse animals receiving general anesthesia with either isoflurane or propofol. The same effect ...

Developed in collaboration with the Michael J. Fox Foundation, homozygous Lrrk2 knockout (KO) rats develop mild histological abnormalities in peripheral organs, most notably in the kidney, but also ...