Genetic studies have revealed many genes linked to both common and rare disease, but to understand how those genes bring about disease and use those insights to help develop therapies, scientists need ...

The scope of human cell type atlases widened considerably today. Formerly, landscapes of individual cell types were largely confined to single organs. But now, thanks to four single-cell RNA ...

Researchers created a DIA-MS atlas of 13,609 proteins across 2,856 samples from fetal, healthy adult, paired non-tumor, and ...

In recent years, a virtual tidal wave of studies linking the expression of certain genes to complex diseases as varied as cancer and diabetes has raised hopes for major advances in medical treatment ...

Protein turnover is critical to cellular physiology as well as to the growth and maintenance of tissues. The unique synthesis and degradation rates of each protein help to define tissue phenotype, and ...

Housekeeping protein-coding genes are stably expressed genes in cells and tissues that are thought to be engaged in fundamental cellular biological functions. They are often utilized as normalization ...

The average adult male has around 36 trillion cells in their body, while average adult females have 28 trillion, researchers have found. Unexpectedly, the mass of small cells in our bodies, such as ...

Traditional-tissue engineering approaches (Panel A) seed cells onto a three-dimensional biomaterial scaffold that serves as a framework for new tissue development (i). The scaffold degrades as new ...