This study provides novel insights into the elongation dynamics of eukaryotic cells and the counteracting mechanisms in place to reduce translation defects during protein synthesis. "Understanding the ...

Elongation, a crucial step in the translation process of protein synthesis, gets disrupted by amino acid sequences with an abundance of N-terminal aspartic and glutamic acid residues in eukaryotic ...

Nuclear-encoded regulatory proteins control mitochondrial translation. A few, however, are encoded by the mitochondrial DNA (mtDNA) and are produced by the mitochondrial translation machinery.

Shihui Liu, Christopher Bachran, Pradeep Gupta, Sharmina Miller-Randolph, Hailun Wang, Devorah Crown, Yi Zhang, Alexander N. Wein, Rajat Singh, Rasem Fattah, Stephen H. Leppla Proceedings of the ...

The biochemical function of the potyviral P3 protein is not known, although it is known to regulate virus replication, movement, and pathogenesis. We show that P3, the putative virulence determinant ...