A Purdue University team has discovered a new therapeutic target for triple-negative breast cancer. The research, led by Kyle Cottrell, an assistant professor of biochemistry, spotlights ...

Cancer’s strongest gene switches push DNA into damaging overdrive, creating repeated breaks and repairs that may fuel tumor ...

WEST LAFAYETTE — A Purdue University research team has identified a new target for treating triple-negative breast cancer, a particularly deadly form of the disease that currently lacks targeted ...

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic tangles overwhelm normal repair pathways, cells flip on a fast but error-prone ...

A Purdue University team led by Kyle Cottrell has discovered a new therapeutic target for triple-negative breast cancer. Triple-negative breast cancer is a particularly deadly form of breast cancer ...

Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer. Every day, billions of cells in your body ...

New study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most powerful genetic "on switches" in cancer cells, called super-enhancers, drive ...

A DNA nano-harvester stays on its track inside tumor cells, measuring cancer aggressiveness by detecting a key microRNA biomarker. (Nanowerk Spotlight) Detecting a cancer-linked microRNA inside a ...