The implementation of distinct gene expression profiles is essential for animal development and physiology. Post-transcriptional silencing by small regulatory RNAs such as miRNAs plays essential roles ...

A key question that remains in biology and biophysics is how three-dimensional tissue shapes emerge during animal development. Research teams have now found a mechanism by which tissues can be ...

Donna L. Farber is a professor of surgical sciences, microbiology and immunology at Columbia University Irving Medical Center in New York City, New York, USA. Early in the pandemic, my team spotted ...

In a study published in the US journal Science Advances, a single cell type map of human tissues is presented. An open access atlas has been launched with more than 250,000 interactive plots to allow ...

Scientists in Japan have created hybrid plant-animal cells, essentially making animal cells that can gain energy from sunlight like plants. The breakthrough could have major benefits for growing ...

Bioengineers have created miniature intestines in a dish that match up anatomically and functionally to the real thing better than any other lab-grown tissue models. The biological complexity and ...

Tissue optical clearing is a fundamental technique that enhances light penetration deep into biological samples by reducing light scattering through refractive index homogenization. This process ...

To accurately diagnose and treat diseases, doctors and researchers need to see inside bodies. Medical imaging tools have come a long way since the humble x-ray, but most existing tools remain too ...

3D surface of the fruit fly wing disc before (left) and after (right) eversion. Highlighted in blue is the pouch region, which transforms from a radially symmetric dome into a curved fold by ...