The human liver plays a pivotal role in drug metabolism, largely attributable to the diverse family of UDP-glucuronosyltransferases (UGTs) that catalyse glucuronidation reactions. This conjugation ...
Eli Lilly’s blockbuster diabetes and obesity drug improved liver scarring in a mid-stage study of the liver disease MASH, adding to positive data announced earlier this year. The study tested three ...
The liver is the principal site of the body's drug metabolism, so it isn't surprising that drug-induced liver injury (DILI) can occur. However, despite the common use of medications in today's society ...
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Weight-loss drugs like Wegovy could help serious liver condition that has no cure-all treatment
The key ingredient in blockbuster weight-loss drugs could help people manage a serious liver condition before it becomes life-threatening, a new trial has found. The results, published on Wednesday in ...
Researchers at the University of Barcelona found that combining pemafibrate and telmisartan significantly reduces liver fat and cardiovascular risks in MASLD models. The drug duo works better together ...
Metabolic dysfunction-associated steatohepatitis (MASH) is a silent liver disease that is caused by fat buildup, inflammation ...
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