Exonuclease action of replicative polymerase gamma drives damage-induced mitochondrial DNA clearance
How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...
The PIF/Harbinger-derived ADF-IL protein recruits KAT2B to drive its nuclear translocation and local chromatin acetylation, ...
Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...
High CDC20 expression promotes aneuploid cancer cell sensitivity to spindle assembly checkpoint (SAC) inhibition by ...
In adolescent male mice, hippocampal neurogenesis regulates dominance behavior independently of anxiety, revealing a novel function for this cellular process. Natural variations in hippocampal ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Homologous recombination is a largely ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Ferroptosis, an iron-dependent form of ...
Mutant p53 regulates a distinct gene set by a mode of genome occupancy that is shared with wild type
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. To directly examine the interplay between ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Recent studies argue for a novel concept of ...
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