tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

A molecule called tRNA is an essential component of the human genome that acts as a translator. When researchers and clinicians investigate the genome's relation to disease, they have traditionally ...

In addition, some patent applications directed to the diagnosis or treatment taking note of mitochondrial tRNA have been filed. “1) A method for diagnosing type 2 diabetes by chemical modification of ...

Scientists analyze 4.3 billion dipeptides across species to trace genetic code evolution and early protein development.

Raghu R. Chivukula, MD, PhD, a physician-investigator in the Departments of Medicine & Surgery and the Center for Genomic Medicine at Massachusetts General Hospital and Harvard Medical School, is the ...

David G. Longstaff, Ross C. Larue, Joseph E. Faust, Anirban Mahapatra, Liwen Zhang, Kari B. Green-Church, Joseph A. Krzycki Proceedings of the National Academy of ...

Alltrna is the latest in a growing number of startups with plans to develop therapies based on transfer RNA (tRNA), a family of RNA molecules that play a vital role in building proteins. The Cambridge ...