Scientists at UCSF invented a microscopic “womb” material for growing artificial organs (organoids) from scratch.
Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, ...
The trillions of microbes in our gastrointestinal tract, known as the gut microbiome, are crucial to the body; the gut microbiome aids in digestion, nutrient absorption, and influences our health in ...
While in vivo animal models are commonly employed for pharmacokinetic studies, they are often expensive, low in throughpu,t and typically fail to accurately replicate key characteristics of the human ...
Gut organoids are three-dimensional (3D), stem cell-derived structures that mimic the cellular composition and functions of the human gastrointestinal (GI) tract. By replicating digestive physiology ...
What am I looking at? This video shows actin at work in a growing intestinal organoid. The video is depth-coded for color, which means that cooler colors like blue and purple are closer to the viewer ...
A team led by Prof. Dr. Dirk Haller has demonstrated for the first time that defective mitochondria cause injuries in the intestinal epithelium and influence the microbiome. In this microscopic image ...
Lab-grown human tissue successfully repairs damaged intestines in rodent model. Achievement led by experts at Cincinnati Children's moves years-long research effort closer to first-in-human clinical ...
D organoid models are becoming increasingly important in biological research and drug discovery. However, their use remains ...
Cells on the inner surface of the intestine are replaced every few days. But, how does this work? It was always assumed that cells leave the intestinal surface because excess cells are pushed out. In ...