If you receive Microsoft Excel cannot access the file, There are several possible reasons error message you can use the following suggestions to resolve the issue.

Microsoft increased the power and range of its protections against these attacks through configurable limits on Excel's compatibility with specific file types, including some of Excel's own.

Microsoft Office Excel cannot access the file ' [file path]'. There are several possible reasons: • The file name or path does not exist. • The file is being used by another program.