Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. An international team of ...
One in every three FDA-approved drugs targets a single superfamily of receptors dotting the surfaces of human cells. From beta blockers to antihistamines, these essential, life-saving medications ...
Researchers report that redesigning neurokinin-1 receptor (NK1R) antagonists can restore antidepressant-like effects in animal models. Using machine-learning-guided screening, the team identified ...
A new study reveals a critical vulnerability in a brain receptor targeted by a rare autoimmune disease. Researchers have ...
For decades, scientists have investigated the neurokinin-1 receptor (NK1R) as a potential target for treating major depressive disorder. Early studies suggested promise, but enthusiasm faded after ...
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