In 1980, TIME Magazine wrote about interferon as the “if” drug for cancer. Promising studies sparked widespread hope around the potential of the interferon to treat cancer, only if it could deliver ...
A schematic diagram illustrates a proposed mechanism of interferon-γ (IFN-γ)-induced downregulation of tricellulin in salivary epithelial cells. IFN-γ leads to the phosphorylation of signal transducer ...
Data supportive of CX-801’s mechanism of action and the ongoing Phase 1 combination study with KEYTRUDA® (pembrolizumab) - SOUTH SAN FRANCISCO, Calif., Nov. 04, 2025 (GLOBE NEWSWIRE) -- CytomX ...
Molecular Biology of Anaplastic Lymphoma Kinase–Positive Anaplastic Large-Cell Lymphoma PURPOSE: The toxicity associated with adjuvant high-dose interferon-alfa-2b therapy (HDI) for high-risk melanoma ...
Ethris Presents Positive Topline Phase 1 Data with mRNA Lead Candidate ETH47 for Uncontrolled Asthma
Dose-dependent target engagement: ETH47 exhibited a clear dose-dependent production of IFNλ in the nasal lining fluid exceeding predicted therapeutic levels. ETH47 administration also activated the ...
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