Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis ...

An ambitious plan to sequence genomes for 1.85 million eukaryotic species on our planet is underway. It's a massive ...

Genetic variants that cause rare disorders may remain elusive even after expansive testing, such as exome sequencing. The diagnostic yield of genome sequencing, particularly after a negative ...

At a time when large-scale human genome analysis was not yet common, the Tohoku Medical Megabank Organization (ToMMo) launched its genome cohort study. After 10 years of operating this ambitious ...

Rapid precision run-on sequencing (rPRO-seq) may help doctors understand disease states and treatment response in real time. Researchers at Sylvester Comprehensive Cancer Center (FL, USA) have ...

Protein sequencing presents different challenges than nucleic acid sequencing, meaning that proteomics has yet to benefit as much as genomics from the next-generation sequencing revolution. However, ...

Whole genome sequencing in nearly 500,000 UK Biobank participants shows that observed rare and common variants now explain ...

Genome sequencing has been used to determine how much genes influence human characteristics including height and weight, and ...