Decoding the T cell burst: Signature genes predict T cell expansion in cancer immunotherapy

The ability of immune cells—particularly CD8+ T cells—to launch a rapid burst of proliferation inside tumors is key to the ...

Epigenetic reprogramming safely modifies multiple genes in T cells simultaneously for CAR-T therapies

Arc Institute, Gladstone Institutes, and University of California, San Francisco, scientists have developed an epigenetic ...
Nature

Breastfeeding boosts immune cells that protect against breast cancer

Pregnancy and breastfeeding induces the accumulation of specialized immune cells that reduce the chances of breast cancer ...
News-Medical.Net on MSN

Epigenetic editing enables safer and more effective T cell therapies

Arc Institute, Gladstone Institutes, and University of California, San Francisco, scientists have developed an epigenetic ...
Targeted Oncology

T-Cell Engager Toxicities in Solid Tumors: Recognition and Management

T-cell engagers, especially BiTEs, show promise in treating solid tumors by targeting tumor-associated antigens and redirecting T-cell activity. Tarlatamab, targeting DLL3 in SCLC, demonstrated ...
News-Medical.Net on MSN

Researchers uncover TRAT1's central role in T helper cell function

Researchers at the Medical University of Vienna have taken a closer look at a previously largely unknown component of the ...

Attaching 'fake targets' to tumor cells enables antigen-independent immunotherapy

A research team has introduced a novel cancer immunotherapy strategy. This approach involves attaching "fake targets" to ...