Past research has already demonstrated significant links between DENND1B variants and body mass index (BMI) in humans, the team add. Unfortunately, genes associated with obesity are not obvious ...

Dogs carrying DENND1B had about 8% more body fat than those without it. “Studying the dogs showed us something really powerful: Owners of slim dogs are not morally superior.

By comparing the obesity status of the dog to its DNA, they could identify the genes linked to canine obesity. Dogs carrying ...

While all dogs have a gene called DENND1B, the researchers discovered that those with a particular variant of DENND1B—called rs24430444—had approximately 8% more body fat than those without it.

DENND1B was found to directly affect a brain pathway responsible for regulating the energy balance in the body, called the leptin melanocortin pathway.

In fact, it might be best not to consider meddling with DENND1B for the sake of tackling obesity. "These genes are not immediately obvious targets for weight-loss drugs, because they control other ...

DENND1B was found to directly affect a brain pathway responsible for regulating the energy balance in the body, called the leptin melanocortin pathway.

Genetic variants associated with canine obesity, particularly DENND1B, are also associated with obesity in humans, new research revealed. Notably, labrador retrievers carrying DENND1B had around 7 ...

DENND1B gene, and the researchers found that this gene is also linked with obesity in people. DENND1B was found to directly affect a brain pathway responsible for regulating the energy balance in ...

Variants in DENND1B also increased the likelihood of both rare and common forms of human obesity caused by genetics. Additional work revealed that DENND1B can directly affect a crucial pathway in the ...

The genetic variant was found to directly affect the so-called 'leptin melanocortin pathway' in the brain, responsible for regulating hunger. Dogs with a genetic mutation to the DENND1B gene had ...

DENND1B gene, and the researchers found that this gene is also linked with obesity in people. DENND1B was found to directly affect a brain pathway responsible for regulating the energy balance ...