Dogs carrying DENND1B had about 8% more body fat than those without it. “Studying the dogs showed us something really powerful: Owners of slim dogs are not morally superior.

Past research has already demonstrated significant links between DENND1B variants and body mass index (BMI) in humans, the team add. Unfortunately, genes associated with obesity are not obvious ...

By comparing the obesity status of the dog to its DNA, they could identify the genes linked to canine obesity. Dogs carrying ...

DENND1B was found to directly affect a brain pathway responsible for regulating the energy balance in the body, called the leptin melanocortin pathway.

In fact, it might be best not to consider meddling with DENND1B for the sake of tackling obesity. "These genes are not immediately obvious targets for weight-loss drugs, because they control other ...

While all dogs have a gene called DENND1B, the researchers discovered that those with a particular variant of DENND1B—called rs24430444—had approximately 8% more body fat than those without it.

DENND1B was found to directly affect a brain pathway responsible for regulating the energy balance in the body, called the leptin melanocortin pathway.

DENND1B gene, and the researchers found that this gene is also linked with obesity in people. DENND1B was found to directly affect a brain pathway responsible for regulating the energy balance in ...

Variants in DENND1B also increased the likelihood of both rare and common forms of human obesity caused by genetics. Additional work revealed that DENND1B can directly affect a crucial pathway in the ...

Discover why your dog may be hungry. Learn how the obesity gene impacts both you and your Labrador's appetite.

DENND1B gene, and the researchers found that this gene is also linked with obesity in people. DENND1B was found to directly affect a brain pathway responsible for regulating the energy balance ...

The genetic variant was found to directly affect the so-called 'leptin melanocortin pathway' in the brain, responsible for regulating hunger. Dogs with a genetic mutation to the DENND1B gene had ...