the authors study the guest-responsive structural transformation of single-crystal 3D covalent organic frameworks at room and high temperatures and identified nine distinct conformational isomers.

In this work we investigate how proline isomerization in disorder-based protein interactions imposes conformational selection in binding ... and structural properties that govern proline ...

Department of Chemical Engineering, Texas Tech University, P.O. Box 43121, Lubbock, Texas 79409-3121, United States ...

In this mini-review, we take a look into the progress of apigenin and genistein, which are isomers, in treating PCa in the past decade. While possessing very similar structure, these two isomers can ...

Recent years have seen several hybrid simulation methods for exploring the conformational space of proteins and their complexes or assemblies. These methods often combine fast analytical approaches ...

In this paper, we set out to gain further insights into the proteolytic mechanism of γ-secretase by using two complementary approaches to sample the conformational landscape of its catalytic subunit.