technologynetworks

Transform MSC Research With Real-Time, Non-Invasive Differentiation Monitoring

Researchers studying mesenchymal stem cells (MSCs) face significant challenges with traditional endpoint assays that provide only limited snapshots of the differentiation process. The inability to ...
Science Daily

DNA aptamer finds novel application in regulating cell differentiation

Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine. Guiding iPSCs toward a target cell line has garnered much ...
Risk

The efficient application of automatic differentiation for computing gradients in financial applications

Automatic differentiation (AD) is a practical field of computational mathematics that is of growing interest across many industries, including finance. The use of reverse-mode AD is particularly ...
Labroots

Improved differentiation of stem cell-derived neurons and downstream applications through the reduction of progenitor proliferation with CultureOne™ Supplement

Neurons derived from human pluripotent stem cells (hPSCs) and primary rodent neurons both are excellent resources for disease modeling and drug screening. Human PSCs derived neural stem cells (NSCs) ...
Risk

Fast stochastic forward sensitivities in Monte Carlo simulations using stochastic automatic differentiation (with applications to initial margin valuation adjustments)

In this paper, we apply stochastic (backward) automatic differentiation to calculate stochastic forward sensitivities. A forward sensitivity is a sensitivity at a future point in time, conditional on ...