Discover the innovative TECHNO platform for full-length gene humanisation, enhancing models for human gene function.
The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...
Researchers at The University of Tokyo developed TECHNO, a two-step genome editing strategy that replaces entire mouse loci ...
Understanding human gene function in living organisms has long been hampered by fundamental differences between species.
Understanding human gene function in living organisms has long been hampered by fundamental differences between species. Although mice share most ...
Researchers have created the most comprehensive map to date of DNA elements that regulate gene activity, nearly tripling the ...
Scientists at UNIGE Faculty of Medicine show how genetic switches activate then deactivate the genes responsible for embryonic development. Their findings, published in Nature Communications, decipher ...
In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...
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